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Guarino, 1998

High-pH RP fractionation was performed at a flow rate of 0.6 mL/min with a gradient starting at 5% B for 2 min, increased to 50% B in 12 min, to 70% B within 0.5 min, and held for 6.5 min

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Liver function is rechecked every 4 to 6 sessions

Bredesens groundbreaking research has helped explain the biological mechanisms behind memory loss

His innovations include early use of buprenorphine to curb opioid cravings